Clinical Trials & Registries

The PADIT study COMPARED whether a center-wide policy of incremental antibiotic therapy reduced CIED infection rate compared to a policy of conventional antibiotic prophylaxis in high-risk patients undergoing arrhythmia device procedures.

Japanese Lead Extraction (J-LEX) Registry is an observational nationwide registry assessing acute success rate at discharge and the complications associated with transvenous lead extraction.

The European Lead Extraction ConTRolled Registry (ELECTRa), was a prospective registry of consecutive transvenous lead extraction (TLE) procedures conducted by the European Heart Rhythm Association (EHRA) in order to identify the safety and efficacy of the current practice of TLE.

World-wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT) was a randomized, controlled clinical trial to assess the safety and efficacy of an absorbable, antibiotic-eluting envelope in reducing the incidence of infection associated with CIED implantations.

The AdaptResponseStudy aimed to demonstrate whether Cardiac Resynchronization Therapy (CRT) devices that use the AdaptivCRT® (aCRT) algorithm have a superior outcome of primary and secondary measures compared to standard CRT devices in CRT-indicated patients with normal atrio-ventricular conduction and left bundle branch block.